What is the SURMOUNT-1 Study? A Breakthrough for Mounjaro and Weight Loss

As obesity rates continue to rise in the UK and globally, more people are looking for safe, effective and trusted solutions to support their weight loss journey. One of the most promising developments in recent years is the introduction of Mounjaro (tirzepatide), a new weight loss medication that has gained attention thanks to groundbreaking research particularly the SURMOUNT-1 study.

At Happy Pharmacy, we’re committed to providing access to regulated, trusted treatments through convenient online consultations, ensuring our patients can begin their weight loss journeys safely and confidently. In this blog, we explore what the SURMOUNT-1 study revealed about Mounjaro, how it works, and how UK patients can now access it online through regulated pharmacies like ours.

What is Mounjaro?

Mounjaro (tirzepatide) is a once-weekly injectable medication originally developed to manage type 2 diabetes. It mimics two key hormones GLP-1 (glucagon like peptide1) and GIP (glucose dependent insulinotropic polypeptide) to help regulate appetite, blood sugar, and insulin levels. But what truly sparked interest in Mounjaro was its powerful weight loss effects observed during clinical trials.

As of 2024, Mounjaro has received approval from the MHRA (Medicines and Healthcare products Regulatory Agency) in the UK for use in chronic weight management in adults with obesity or those who are overweight with weight-related health problems.

The SURMOUNT-1 Study: A Milestone in Obesity Treatment

The SURMOUNT-1 trial is a randomised, double-blind, placebo-controlled study that evaluated Mounjaro’s effectiveness in adults with obesity or overweight, without type 2 diabetes. The goal was to assess weight loss outcomes over a 72-week period.

Key Facts About the Study:

• Participants: 2,539 adults with obesity (BMI ≥30) or overweight (BMI ≥27) with at least one weight-related condition (e.g., high blood pressure, high cholesterol).

• Duration: 72 weeks

• Doses Tested: 5 mg, 10 mg, and 15 mg of tirzepatide, administered once weekly.

• Control: Compared against a placebo group

• Lifestyle Intervention: All participants received lifestyle support, including guidance on healthy eating and physical activity.

How Much Weight Did People Lose with Mounjaro?

The results were remarkable and have reshaped how medical professionals view obesity treatment:

Additional Highlights:

• Over 85% of people on the highest dose (15 mg) lost more than 15% of their body weight.

• Nearly one third lost 25% or more, a result previously only seen with bariatric surgery. 

• Mounjaro significantly reduced waist circumference, cholesterol levels, and other metabolic risk factors.

These findings make SURMOUNT-1 one of the most successful weight loss trials in recent history and cement Mounjaro’s status as a trusted, evidence based treatment for obesity.

Why Mounjaro Works So Well for Weight Loss

Unlike older weight loss medications, Mounjaro targets two hormones (GLP-1 and GIP), which work together to:

• Reduce appetite

• Slow gastric emptying (making you feel fuller longer)

• Regulate insulin and reduce blood sugar

• Promote fat burning while preserving muscle mass

This dual-action approach gives Mounjaro a unique edge, helping patients not only lose more weight but maintain muscle and metabolic health.

Accessing Mounjaro in the UK: Trusted and Regulated

As of 2024, Mounjaro is approved in the UK for weight loss and is available through regulated online pharmacies such as Happy Pharmacy.

At Happy Pharmacy, we make it easy and safe to access Mounjaro through trusted online consultations with a registered healthcare professional. Once approved, patients can receive their prescription via secure delivery, avoiding the need to visit a clinic in person.

Our Service Includes:

• Fast, confidential online consultations

• UK GPhC regulated prescribers and pharmacists

• Access to authentic Mounjaro with cold chain delivery

• Ongoing support and expert advice

We understand that weight loss is a journey, and we’re here to support you every step of the way with trusted, professional care.

Is Mounjaro Right for You?

Mounjaro is suitable for adults with:

• A BMI of 30 or higher, or

• A BMI of 27 or higher with a weight-related condition such as type 2 diabetes, hypertension, or sleep apnoea

It’s important to note that Mounjaro is not a cosmetic weight loss aid. It is a medically supervised treatment for people who have struggled to lose weight through diet and exercise alone.

What to Expect with Mounjaro

Patients who begin Mounjaro therapy should be prepared to:

• Inject the medication once a week, at home

• Make lifestyle adjustments (including diet and physical activity)

• Follow up with healthcare providers to monitor progress and side effects

The most common side effects include nausea, diarrhoea, constipation, and decreased appetite. These are typically mild and temporary, especially when the dosage is increased gradually.

The Importance of a Trusted, Regulated Online Pharmacy

With the rise of online pharmacies, it’s crucial to choose a GPhC-registered, regulated, and trusted provider like Happy Pharmacy. Unfortunately, the internet is rife with counterfeit medications and unlicensed sellers.

At Happy Pharmacy, we guarantee:

• MHRA compliant sourcing

• Full cold chain delivery for temperature-sensitive medications like Mounjaro

• Online consultations with licensed professionals

• Ongoing medical advice and aftercare

Why Choose Happy Pharmacy?

Happy Pharmacy combines professional care with modern convenience. Here’s what sets us apart:

✅ Fully regulated UK online pharmacy
✅ Trusted by thousands of patients nationwide
✅ Convenient online consultations without waiting rooms
✅ Fast, discreet, and secure delivery
✅ Expert advice tailored to your weight loss journey

We believe everyone deserves access to safe and effective weight loss treatments like Mounjaro, without barriers or stigma.

Final Thoughts: A New Era for Weight Loss in the UK

The SURMOUNT-1 study has changed the landscape of obesity treatment, proving that significant, sustainable weight loss is possible without surgery. Mounjaro represents a powerful new tool in the fight against obesity one that is now available to UK patients through regulated online pharmacies like Happy Pharmacy.

If you’re ready to take control of your health and explore medically supported weight loss, speak to our trusted team today through our quick and confidential online consultation process.

References

1. NEJM (New England Journal of Medicine). Tirzepatide Once Weekly for the Treatment of Obesity SURMOUNT-1.

2. MHRA Guidance on Mounjaro Approval

3. NHS: Obesity Treatment Overview
   

4. Eli Lilly UK – Mounjaro for Weight Loss